Alison McCormick, Ph.D.
Professor
Department of Pharmacy
Touro University California
Alison McCormick is an assistant professor of pharmaceutical sciences at the Touro University California College of Pharmacy. She received a Ph.D. from the University of California, and completed her postdoctoral work at the Stanford University School of Medicine. Dr. McCormick has worked on the development of plant-made vaccines, and an individualized cancer vaccine for non-Hodgkins lymphoma. She has collaborated extensively with other research groups and regularly employs molecular biology, protein chemistry and immunology techniques in the production and testing of vaccines.
"The focus of my research has been pandemic preparedness and rapid response vaccine development, using Tobacco Mosaic virus as a subunit vaccine carrier. TMV is a self-assembling +strand RNA plant virus with excellent uniformity, ease of recovery and immune activating characteristics that make it ideal as a safe vaccine delivery vector. Early on in this project, we used molecular evolution to generate at TMV subtype that had improved vaccine characteristics compared to wildtype TMV. We then used the improved TMV to generate vaccines of against a number of different infectious disease targets. I have been working on the validation of Influenza A/B vaccines by preclinical efficacy testing. We have expanded this to develop a universal flu vaccine, with the goal of improving protection against non-homologous strains, and increasing the duration of protection beyond annual vaccinations. I have collaborations with several other labs to develop vaccirnes against other important human pathogens, like plague, tularemia, Pseudomonas aeruginosa and COVID19. Throughout this work, I have been mentoring students, with hands on training in the lab. My role has been to solidify basic concepts in math, biology and chemistry to into working skills and problem solving skill, in order to prepare our students for the changing needs of the pharmaceutical sciences workforce."
Areas of Expertise
Vaccines and preclinical testing
Education
- Iowa State University at Ames, Bachelor of Science in Biological Psychology
- University of California at San Diego, Ph. D in Physiology and Pharmacology
- Stanford University School of Medicine, Postdoctoral fellow
In The News
Touro University wins grant to use tobacco plants to improve health, Daily Republic